4. DNA damage induced by diet
نویسندگان
چکیده
Franco Dani Campos-Pereira, Ana Cristina Prado Veiga-Menoncello, and Maria Aparecida Marin-Morales Laboratório de Mutagênese Ambiental (LMA), Universidade Estadual Paulista – UNESP Avenida 24-A, no 1515, Bela Vista, CEP 13506-900, Rio Claro, São Paulo, Brazil Departamento de Biologia Estrutural e Funcional IB, Universidade Estadual de Campinas UNICAMP, Av. Bertrand Russel, s/no, CEP 13083-865, Campinas, São Paulo, Brazil
منابع مشابه
DNA Damage in Leukocytes from Fanconi Anemia (FA) Patients and Heterozygotes Induced by Mitomycin C and Ionizing Radiation as Assessed by the Comet and Comet-FISH Assay
Background: Lymphocytes of Fanconi anemia (FA) show an increased sensitivity to the alkylating agents such as mitomycin C (MMC), but their responses to gamma-irradiation is controversial. The extent of DNA damage in leukocytes of FA patients following irradiation and MMC treatment was studied at cellular and single chromosome level. Methods: DNA damage induced by gamma-rays and MMC was measure...
متن کاملAntioxidant capacity and radioprotective properties of the flavonoids galangin and kaempferide isolated from Alpinia galanga L. (Zingiberaceae) against radiation induced cellular DNA damage
Background: Alpinia galanga L. belonging to the family Zingiberaceae is widely grown in the state of Kerala, India. They are effective antioxidant and free radical scavenger under both in vitro and in vivo condition. The efficacy of the isolated flavonoids in conferring protection from radiation induced damages to genomic DNA was studied. Materials and Methods: The bioflavonoids, galangin and k...
متن کاملP-65: Nitrosative Stress, Lipid and Carbonyl Groups Peroxidations in Long Time-Induced Varicocele; Association with Sperms DNA Damage in Rats
Background: The pathophysiology of the varicocele has received considerable study, both in humans and in animal models. The sperm DNA damage and related oxidative stress have been identified as significant cause of male infertility. Present study was designed to evaluate the testicular nitric oxide (NO) generation, lipid and carbonyl groups (CGs) peroxidation and to analyze related sperm DNA da...
متن کاملP-226: American Ginseng Effects on Damage Induced by Cyclophosphamide in The Nuclei of Rat Sperm
Background: Oxidative stress occurs when the oxidative homeostasis is damage. Excessive ROS are generated and this reaction has been proposed to produce marked damage to the structure and function of sperm. Materials and Methods: This study was designed to investigate the protective effects of of American Ginseng against cyclophosphamide - induced damage in the rat sperm. For this experiment, t...
متن کاملStudies on electron beam induced DNA damage and repair kinetics in lymphocytes by alkaline comet assay
Background: Exposure to ionizing radiation is known to induce oxidative stress followed by damage to critical biomolecules like lipids, proteins and DNA through radiolysis of cellular water. Since radiation has been widely used as an important tool in therapy of cancer, the detailed investigation regarding the DNA damage and repair kinetics would help to predict the radiation sensitivity of cel...
متن کاملP-62: Damage to Sperm DNA and Protamine Deficiency Induced by Risperidone in NMRI Mice
Background: Antipsychotic medication use is a common cause of hyperprolactinemia that shown to have adverse effects on male fertility. Risperidone is a combined serotonin/dopamine receptor antagonist that can cause elevations in prolactine level. Its mechanism of cytotoxic effects on testicular germ cells is not fully understood. In the present study we sought to elucidate the impact of risperi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2014